Allelix Genotype Report

Source: HG002.child.g.vcf.gz · Annotators: ClinVar (GRCh37:2026-06-18; GRCh38:2026-06-18), ClinPGx (2026-06-18), GWAS Catalog (2026-06-09), SNPedia (scraped 2026-05-20 (104720 genotypes)), gnomAD (4.1), AlphaMissense (2023.2), CADD (v1.7) · Generated 2026-06-18 20:15 UTC

Informational only. This report is informational research output. It surfaces classifications made by external databases (ClinVar, ClinPGx, …) for variants present in the input genotype file. It is not medical advice and not a diagnosis. Every classification is attributed to its source database; Allelix does not independently classify variants.
Reading This Report

Pseudogene cross-hybridization

Some genes have known pseudogenes with high sequence similarity (e.g., PKD1 has six pseudogenes sharing >97% identity). Array-based genotyping probes can cross-hybridize, producing false genotype calls. If a result seems inconsistent with your health history, confirmatory testing by a different method is recommended.

ClinVar aggregation

ClinVar aggregates submissions from multiple sources. Different submitters may classify the same variant differently, and significance labels may be paired with conditions from a different submitter’s entry. Single-submitter entries carry less weight than expert-panel-reviewed classifications.

Carrier vs. affected

A variant classified as pathogenic in a recessive condition requires two copies to cause disease. If you are heterozygous (one copy), you are a carrier. Carrier status does not typically cause symptoms but may be relevant for family planning.

Confirmatory testing

No genotyping platform is 100% accurate. Clinically significant findings should be confirmed with an independent method before making medical decisions.

Understanding Magnitude Scores

Each annotation source uses its own criteria to assign a magnitude score (0–10) that reflects clinical importance. Higher scores warrant more attention. The score shown in the table is the maximum across all source annotations for that variant.

ClinVar (clinical significance)

9Pathogenic
8Pathogenic (single submitter / no assertion criteria)
7Likely pathogenic
5Uncertain significance / conflicting
4Risk factor / drug response / association
3Likely benign
1Benign

ClinPGx (pharmacogenomic evidence)

9Level 1A — CPIC guideline or FDA label
8Level 1B — strong clinical evidence
6Level 2A — moderate evidence
5Level 2B — moderate (weaker replication)
4Level 3 — low evidence or annotation only

GWAS Catalog (trait associations)

6p < 5×10-8 (genome-wide)
4p < 5×10-6 (suggestive)
3p < 1×10-4 (nominal)

SNPedia (community-curated)

Magnitude is assigned directly by community editors (0–10 scale). Higher scores indicate greater clinical or personal relevance as judged by contributors. See SNPedia’s magnitude documentation for details.

CADD (variant deleteriousness)

CADD PHRED scores rank how deleterious a variant is relative to all possible human SNVs. Higher scores = more likely to be deleterious.

≥ 30Top 0.1% most deleterious
≥ 20Top 1% most deleterious
≥ 10Top 10% most deleterious
< 10Below top 10%

AlphaMissense (missense pathogenicity)

DeepMind’s protein-structure-based pathogenicity prediction for missense variants. Score 0–1; higher = more likely pathogenic.

≥ 0.564Likely pathogenic
0.340 – 0.564Ambiguous
< 0.340Likely benign
Sample
HG002
Format
VCF / gVCF
Build
GRCh38
Variants
276
Bad
39
Good
5
Total Annotations
300
Source-specific thresholds. The global minimum magnitude is 5.0, but lower thresholds apply to: SNPEDIA (mag ≥ 2.0). Some rows below the global threshold may appear from these sources.
Mag▼GeneGTReputeSummary
9CASZ1CTNeutral[GWAS Catalog] Varicose veins
9CDKN2B-AS1AGNeutral[GWAS Catalog +2] Coronary artery / coronary heart disease (including heart attack, angina)
9CDKN2B-AS1GTNeutral[GWAS Catalog] Other chronic ischemic heart disease, unspecified
9IL10CTBad[ClinVar] Hepatitis C virus, susceptibility to
9SYNE2, ESR2AGNeutral[GWAS Catalog] Atrial fibrillation
9PRSS56AGNeutral[GWAS Catalog] Refractive error
9CTLA4 - ICOSAGNeutral[GWAS Catalog +1] Hypothyroidism
9-CGBad[ClinVar] XG BLOOD GROUP SYSTEM, Xg(a-) PHENOTYPE
9FANCACGNeutral[GWAS Catalog] Low tan response
9GCGTNeutral[GWAS Catalog] Vitamin deficiency
9CDKN2B-AS1AGNeutral[GWAS Catalog +1] Coronary artery disease
9ADRA2AAGBad[ClinVar] Lipodystrophy, familial partial, type 8
9FASCTNeutral[GWAS Catalog] Tumor necrosis factor receptor superfamily member 6 levels
8VKORC1GGNeutral[ClinPGx +2] ClinPGx: warfarin — Patients with the rs8050894 GG genotype may require a lower dose of warfarin as compared to patients with the CC genotype. Other genetic and clinical factors may also influence warfarin dosage requirements.
7NPHS1GTC/GBad[ClinVar] Finnish congenital nephrotic syndrome
7MTHFRAGNeutral[ClinPGx +2] Arthritis, Psoriatic;Drug Toxicity;Juvenile Rheumatoid Arthritis;Rheumatoid arthritis
6ABCB1TTNeutral[ClinVar] Tramadol response
6CYP2D6CTNeutral[ClinVar] Tramadol response
6NPC1L1CTNeutral[ClinVar] Statins, attenuated cholesterol lowering by
6ABCB1CTNeutral[ClinVar] Tramadol response
6ABCB1CCNeutral[ClinVar] Tramadol response
6UGT2B7ACNeutral[ClinVar] Tramadol response
6UGT2B7AGNeutral[ClinVar] Tramadol response
6HMGCRCTNeutral[ClinVar] Statins, attenuated cholesterol lowering by
6ABCB1CGNeutral[ClinVar] Tramadol response
6FKBP5CTNeutral[ClinVar +3] Antidepressant drug treatment, accelerated response to
6LAMB2CTNeutral[ClinVar] Corticosteroids response
6COMTAGNeutral[ClinVar] Tramadol response
6COMTTTNeutral[ClinVar] Tramadol response
6ABCB1ATNeutral[ClinVar] Tramadol response
6ABCB1CTNeutral[ClinVar] Tramadol response
6ABCB1TTNeutral[ClinVar] Tramadol response
6CYP2D6CTNeutral[ClinVar] Tramadol response
6ABCB1AGNeutral[ClinVar] Tramadol response
6KIF6AGNeutral[ClinVar] pravastatin response - Efficacy
6OPRM1CCNeutral[ClinVar] Tramadol response
6ABCB1CCNeutral[ClinVar] Tramadol response
6ABCB1CTNeutral[ClinVar] Tramadol response
6ABCB1AGNeutral[ClinVar] Tramadol response
6ABCB1AGNeutral[ClinVar] Tramadol response
6ABCB1CCNeutral[ClinVar] Tramadol response
6DIO1ACNeutral[ClinVar +1] Levothyroxine response
6CYP2D6CTNeutral[ClinVar] Tramadol response
6XRCC1CCNeutral[ClinVar +1] Platinum compounds response - Efficacy
6UGT2B7AGNeutral[ClinVar] Tramadol response
6CYP2D6GTNeutral[ClinVar] Tramadol response
6CYP2D6CTNeutral[ClinVar] Tramadol response
6CYP2D6GTNeutral[ClinVar] Tramadol response
6CYP2D6AGNeutral[ClinVar] Tramadol response
6ABCB1CTNeutral[ClinVar] Tramadol response
6ABCB1CTNeutral[ClinVar] Tramadol response
6ABCB1AGNeutral[ClinVar] Tramadol response
6CYP2D6AGNeutral[ClinVar] Tramadol response
6SCN1ACTNeutral[ClinVar +1] carbamazepine response - Dosage
6ABCB1CTNeutral[ClinVar] Tramadol response
6APOEGTNeutral[ClinVar +1] Warfarin response
6UGT2B7CGNeutral[ClinVar] Tramadol response
6UGT2B7ATNeutral[ClinVar] Tramadol response
6APOECCNeutral[ClinVar] Warfarin response
6ATICCTNeutral[ClinVar +1] methotrexate response - Efficacy
6OPRM1GGNeutral[ClinVar] Tramadol response
6OPRM1TTNeutral[ClinVar] Tramadol response
6OPRM1TTNeutral[ClinVar] Tramadol response
6OPRM1GGNeutral[ClinVar] Tramadol response
6OPRM1GGNeutral[ClinVar] Tramadol response
6UGT2B7CTNeutral[ClinVar] Tramadol response
6ITPAACNeutral[ClinVar +1] peginterferon alfa-2b and ribavirin response - Toxicity
6CYP19A1ACNeutral[ClinVar] Letrozole response
6APOECTNeutral[ClinVar +1] atorvastatin response - Efficacy
6UGT2B7AGNeutral[ClinVar] Tramadol response
6UGT2B7CTNeutral[ClinVar] Tramadol response
6UGT2B7CTNeutral[ClinVar] Tramadol response
6UGT2B7CTNeutral[ClinVar] Tramadol response
6ABCB1ACNeutral[ClinVar] Tramadol response
6ABCB1GGNeutral[ClinVar] Tramadol response
6OPRM1CCNeutral[ClinVar] Tramadol response
6LOXL1TTBad[ClinVar] Exfoliation syndrome, susceptibility to
6CDKN2B-AS1AGBad[ClinVar] Three Vessel Coronary Disease
6IRF5AABad[ClinVar] Systemic lupus erythematosus, susceptibility to, 10
6TCF7L2CCBad[ClinVar] Diabetes mellitus type 2, susceptibility to
6IL1BAGBad[ClinVar] Gastric cancer susceptibility after h. pylori infection
6TCF7L2TTBad[ClinVar +1] Diabetes mellitus type 2, susceptibility to
6STOX1CTBad[ClinVar] Preeclampsia/eclampsia 4
6EPOACBad[ClinVar] Microvascular complications of diabetes, susceptibility to, 2
6USF1CTBad[ClinVar] Hyperlipidemia, familial combined, susceptibility to
6ECE1GTBad[ClinVar] Hypertension, essential, susceptibility to
6ECE1ACBad[ClinVar] Hypertension, essential, susceptibility to
6LOXL1CCBad[ClinVar] Exfoliation syndrome, susceptibility to
6XBP1CGBad[ClinVar] MAJOR AFFECTIVE DISORDER 7, SUSCEPTIBILITY TO
6CNTNAP2AGBad[ClinVar] Autism, susceptibility to, 15
6KCNB2AABad[ClinVar] Colorectal cancer
6AQP7CTBad[ClinVar] OBESITY (BMIQ17), SUSCEPTIBILITY TO
6TBXTAGBad[ClinVar] Neural tube defects, susceptibility to
6MMP3G/GABad[ClinVar] Coronary heart disease, susceptibility to, 6
6USF1AGBad[ClinVar] Hyperlipidemia, familial combined, susceptibility to
6CD244CTBad[ClinVar] Rheumatoid arthritis
6SLC22A4TTBad[ClinVar] Rheumatoid arthritis
6CHI3L1CCBad[ClinVar] Asthma-related traits, susceptibility to, 7
6CAPN10CTBad[ClinVar] Type 2 diabetes mellitus 1, susceptibility to
6RNF212CCBad[ClinVar] Down syndrome
6-CCBad[ClinVar] Obesity
6PTGER2AGBad[ClinVar] Asthma, aspirin-induced, susceptibility to
6-AABad[ClinVar] Obesity
6LGALS2AGBad[ClinVar] Myocardial infarction, susceptibility to
6CD209AGBad[ClinVar] Mycobacterium tuberculosis, susceptibility to
6-GTBad[ClinVar] Colorectal cancer
6CNTNAP2TTBad[ClinVar +1] Autism, susceptibility to, 15
6TCF7L2TTBad[ClinVar +1] Diabetes mellitus type 2, susceptibility to
6HLA-CCTBad[ClinVar +1] HIV-1 VIREMIA, SUSCEPTIBILITY TO
5PADI2GTNeutral[ClinVar] Rheumatoid arthritis;C5441745:Abnormal pulmonary interstitial morphology
5TNFSF15CTNeutral[ClinVar] Leprosy, susceptibility to, 1
5IL1RL2CTNeutral[ClinVar] Ascending aortic dissection
5MGST1GTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5ECPASCTNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5CYP4A22CTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5CYP2D6CGNeutral[ClinVar] not provided
5-CTNeutral[ClinVar] Chronic obstructive pulmonary disease
5RNLSAGNeutral[ClinVar] Family history
5BMAL2AGNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5SLC35F1AGNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5SULT1B1AGNeutral[ClinVar] Levothyroxine response
5CD44CTNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5SLC9A4AGNeutral[ClinVar] Ascending aortic dissection
5APCAGNeutral[ClinVar] Familial colorectal cancer
5P2RY11AGNeutral[ClinVar] Cataplexy and narcolepsy
5HMGCRATNeutral[ClinVar] Low density lipoprotein cholesterol level quantitative trait locus 3
5IL1RL1AGNeutral[ClinVar] Ascending aortic dissection
5SLC24A4GTNeutral[ClinVar] SKIN/HAIR/EYE PIGMENTATION 6, BLOND/BROWN HAIR
5SLCO3A1CCNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5HERC2GGNeutral[ClinVar +1] SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES
5IL18R1GTNeutral[ClinVar] Behcet disease
5UMODAGNeutral[ClinVar] Essential hypertension
5GRIK2CTNeutral[ClinVar] Lip and oral cavity carcinoma
5DCTCTNeutral[ClinVar] Age related macular degeneration 7
5LNX1CTNeutral[ClinVar] Lip and oral cavity carcinoma
5SLC9A4CTNeutral[ClinVar] Ascending aortic dissection
5PPANCTNeutral[ClinVar] Cataplexy and narcolepsy
5TMEM132DCTNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5IL18RAPATNeutral[ClinVar] Ascending aortic dissection
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCCTNeutral[ClinVar] Familial colorectal cancer
5HERC2TTNeutral[ClinVar] SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES
5RNF212AANeutral[ClinVar] RECOMBINATION RATE QUANTITATIVE TRAIT LOCUS 1
5IL1BAGNeutral[ClinVar] Antisynthetase syndrome
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCACNeutral[ClinVar] Familial colorectal cancer
5CYP11B2AGNeutral[ClinVar] Aldosterone to renin ratio, increased
5LIPCCTNeutral[ClinVar] High density lipoprotein cholesterol level quantitative trait locus 12
5TNFACNeutral[ClinVar] Alzheimer disease, protection against
5FAM13ATTNeutral[ClinVar] Chronic obstructive pulmonary disease
5MGST1AANeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5IL1RL1AANeutral[ClinVar] Ascending aortic dissection
5CYP2C8CTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5SAMD4ACTNeutral[ClinVar] Lip and oral cavity carcinoma
5APCCTNeutral[ClinVar] Familial colorectal cancer
5APCGTNeutral[ClinVar] Familial colorectal cancer
5PADI2CTNeutral[ClinVar] Rheumatoid arthritis;C5441745:Abnormal pulmonary interstitial morphology
5AHSGGTNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5AHSGAGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5NOS3CTNeutral[ClinVar] Metabolic syndrome, susceptibility to
5NOD2AGNeutral[ClinVar] Leprosy, susceptibility to, 1
5HAO1AGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5PADI4CTNeutral[ClinVar] Rheumatoid arthritis
5IL18R1ACNeutral[ClinVar] Ascending aortic dissection
5IL1RL2ACNeutral[ClinVar] Ascending aortic dissection
5DIO2CTNeutral[ClinVar] Levothyroxine response
5DIO2AGNeutral[ClinVar] Levothyroxine response
5HAO1AGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5RAB2AGGNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5SDC3AGNeutral[ClinVar] Obesity, association with
5P2RY11AGNeutral[ClinVar +1] Cataplexy and narcolepsy
5ANKRD17CTNeutral[ClinVar] Lip and oral cavity carcinoma
5BMP2AGNeutral[ClinVar] Lung cancer
5LDHATTNeutral[ClinVar] decreased blood alpha-hydroxyisovalerate levels
5HAO1AGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5APCCTNeutral[ClinVar] Familial colorectal cancer
5APCCTNeutral[ClinVar] Familial colorectal cancer
5APCAANeutral[ClinVar] Familial colorectal cancer
5APCCCNeutral[ClinVar] Familial colorectal cancer
5ABOCCNeutral[ClinVar] ABO blood group system
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCCGNeutral[ClinVar] Familial colorectal cancer
5APCCTNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCATNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5OR2J3AGNeutral[ClinVar] C3HEX, ability to smell
5CD44AGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5CD44ATNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5CD44CGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5APCGGNeutral[ClinVar] Familial colorectal cancer
5HLA-GGATTTGTTCATGCCT/GATTTGTTCATGCCTNeutral[ClinVar] Post-COVID-19 disorder
5AGXT2CTNeutral[ClinVar] Beta-aminoisobutyric acid, urinary excretion of
5OR2J3AGNeutral[ClinVar] C3HEX, ability to smell
5CYP2C8CTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5IL18R1CTNeutral[ClinVar] Ascending aortic dissection
5CD44AGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5RNF212GGNeutral[ClinVar] RECOMBINATION RATE QUANTITATIVE TRAIT LOCUS 1
5APCAANeutral[ClinVar] Familial colorectal cancer
5EIF3GAGNeutral[ClinVar] Cataplexy and narcolepsy
5CASP8TAGTAAG/TNeutral[ClinVar] Lung cancer, protection against
5-AGNeutral[ClinVar] Familial colorectal cancer
5ARNT2CTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCCTNeutral[ClinVar] Familial colorectal cancer
5-AGNeutral[ClinVar] Chronic osteomyelitis
5APCCTNeutral[ClinVar] Familial colorectal cancer
5CXCL8ATNeutral[ClinVar] Cholangiocarcinoma
5APCAGNeutral[ClinVar] Familial colorectal cancer
5ABCC1GTNeutral[ClinVar] Familial cancer of breast
5SLC9A4GTNeutral[ClinVar] Ascending aortic dissection
5-ATNeutral[ClinVar] Familial colorectal cancer
5-AGNeutral[ClinVar] Familial colorectal cancer
5XRCC1CGTGT/CNeutral[ClinVar] Laryngeal squamous cell carcinoma
5TNFSF15CTNeutral[ClinVar] Leprosy, susceptibility to, 1
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCCCNeutral[ClinVar] Familial colorectal cancer
5APCGTNeutral[ClinVar] Familial colorectal cancer
5APCCTNeutral[ClinVar] Familial colorectal cancer
5APCCCNeutral[ClinVar] Familial colorectal cancer
5APCAANeutral[ClinVar] Familial colorectal cancer
5FKBP5CTNeutral[ClinVar] Susceptibility to severe depressive disorder
5FKBP5AGNeutral[ClinVar] Susceptibility to severe depressive disorder
5CREB5GTNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5CCDC3CTNeutral[ClinVar] Lip and oral cavity carcinoma
5IL18R1ACNeutral[ClinVar] Behcet disease
5SLC9A4CTNeutral[ClinVar] Ascending aortic dissection
5FUT2GGNeutral[ClinVar] Familial Otitis Media
5IL1RL1CTNeutral[ClinVar] Ascending aortic dissection
5ABOGGNeutral[ClinVar] ABO blood group system
5APCCTNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5ABOGGNeutral[ClinVar] ABO blood group system
5APCGTNeutral[ClinVar] Familial colorectal cancer
5APCCGNeutral[ClinVar] Familial colorectal cancer
5ASIPGGNeutral[ClinVar] SKIN/HAIR/EYE PIGMENTATION 9, DARK/LIGHT HAIR
5HAO1CTNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5PRSS2AGNeutral[ClinVar] Pancreatitis, chronic, protection against
5KITLGCTNeutral[ClinVar] SKIN/HAIR/EYE PIGMENTATION 7, DARK/LIGHT SKIN
5SLC2A9CTNeutral[ClinVar] Uric acid concentration, serum, quantitative trait locus 2
5PINK1AGNeutral[ClinVar] Leprosy, susceptibility to, 1
5CYP4Z1AGNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5IL1RL1CTNeutral[ClinVar] Ascending aortic dissection
5FUT2TTNeutral[ClinVar] Familial Otitis Media
5FKBP5ACNeutral[ClinVar] Susceptibility to severe depressive disorder
5CD44ATNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5CD44AGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5SPNS2GGNeutral[ClinVar] Vascular endothelial growth factor (VEGF) inhibitor response
5SLC2A9AGNeutral[ClinVar] Uric acid concentration, serum, quantitative trait locus 2
5APCACNeutral[ClinVar] Familial colorectal cancer
5BGLAPAGNeutral[ClinVar] Nephrolithiasis, calcium oxalate
5-AGNeutral[ClinVar] Chronic osteomyelitis
5APCAGNeutral[ClinVar] Familial colorectal cancer
5APCAGNeutral[ClinVar] Familial colorectal cancer
5NOD2AGNeutral[ClinVar] Leprosy, susceptibility to, 1
5MGST3GTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5APCTTNeutral[ClinVar] Familial colorectal cancer
5IL18RAPCTNeutral[ClinVar] Ascending aortic dissection
5-AGNeutral[ClinVar] Chronic obstructive pulmonary disease
5HERC2CCNeutral[ClinVar] SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES
5MGST1GTNeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5MGST3AANeutral[ClinVar] Pulmonary disease, chronic obstructive, susceptibility to
5FKBP5CGNeutral[ClinVar] Susceptibility to severe depressive disorder
5CDKN2B-AS1CGNeutral[ClinVar] Three Vessel Coronary Disease
5CNTN4CTNeutral[ClinVar] Lip and oral cavity carcinoma
3TP53CCGood[SNPedia] SNPedia: Live 3 years longer. Chemotherapy is more effective.
2ABCC11CTGood[SNPedia] SNPedia: Wet earwax. Slightly better body odour.
2ADIPOQGTGood[SNPedia] SNPedia: Slightly lower risk of breast cancer
2FOXO3GTGood[SNPedia] SNPedia: One copy of a longevity gene. Slightly increased lifespan.
2TBX21CCNeutral[SNPedia] SNPedia: 2.1x risk for Aspirin Induced Asthma. But possibly lower risk of lupus and intractable Graves' disease.
2APOBAGBad[SNPedia] SNPedia: increased risk in men for biliary conditions
2ITGB3CTBad[SNPedia] SNPedia: MI risk, aspirin resistance
2HTR2ACTGood[SNPedia] SNPedia: Normal risk of sexual dysfunction when taking SSRI Antidepressants.